Prepregnancy obesity and birth defects: what’s next?

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Prepregnancy obesity and birth defects: what's next?

Recent data from the National Health and Nutrition Examination Survey for the years 2007–2008 showed that over a third of women ages 20–39 y in the United States are obese [defined as a body mass index [in kg/m] 30] (1). The frequency of obesity among women of childbearing age makes it critical to understand the effects of prepregnancy obesity on maternal and infant outcomes. Prepregnancy obesi...

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Prepregnancy obesity and birth defects in Rhode Island.

Obesity is a chronic condition linked with diabetes, stroke, coronary artery disease, and hypertension. 1 The estimated prevalence of obesity in the United States (26.7%) and Rhode Island (24.9%) has increased over the past decades. Obese women are at increased risk for pregnancy complications and poor birth outcomes. Specifically, prepregnancy obesity has been associated with birth defects, es...

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Prepregnancy obesity as a risk factor for structural birth defects.

OBJECTIVE To describe the relation between maternal obesity, overweight and underweight status, and 16 categories of structural birth defects. DESIGN An ongoing multisite, case-control study. Clinical geneticists reviewed all of the cases, excluding those that had or were strongly suspected to have a single-gene disorder or chromosomal abnormality. Mothers with preexisting diabetes were also ...

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Maternal obesity and risk for birth defects.

OBJECTIVE Several studies have shown an increased risk for neural tube defects associated with prepregnancy maternal obesity. Because few recent studies have examined the relation between maternal prepregnancy obesity and overweight and other birth defects, we explored the relation for several birth defects and compared our findings with those of previous studies. METHODS We conducted a popul...

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Prepregnancy obesity and pregnancy outcome.

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2010

ISSN: 0002-9165,1938-3207

DOI: 10.3945/ajcn.2010.29666